Once diagnosed, ALS patients gradually experience muscle atrophy and paralysis, eventually losing the ability to speak, swallow, and breathe, leading to death. The average survival period is only 2 to 5 years after diagnosis.
ALS is considered one of the top five incurable diseases worldwide, with no significant breakthroughs in nearly 200 years. Its etiology remains unclear, and there are no effective treatments available to halt its progression, resulting in a zero cure rate. Other neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease affect more than 15 million people in China. Conquering ALS could lead to significant breakthroughs in the treatment of all neurodegenerative diseases.